Decoding the tumor genetic blueprint
Mapping the tumor microenvironment
High tech tools of reverse engineering
Designing the targeted counter attack
007skaty Cancer cells reprogram immune cells, blood vessels, and fibroblasts into a protective shield that blocks therapies and fuels growth.
007skaty Cancer cells release VEGF proteins to force nearby blood vessels to feed them.
007skaty Decode the cellular disguises to learn how breast cancer cells hide from the immune system.
Tumor blood vessels: Blood vessels grown by tumors are highly disorganized, leaky, and twisted compared to the neat highways of healthy tissue.
Which healthy cells are frequently hijacked by breast tumors to produce collagen and build a physical protective barrier?
What term refers to the complex ecosystem of normal cells, blood vessels, and signaling molecules surrounding a tumor?
What is the biological term for the formation of new blood vessels that tumors use to feed themselves?
Which signaling protein do breast cancer cells release to stimulate nearby blood vessels to grow toward the tumor?
What type of immune cells are primarily responsible for recognizing and directly destroying abnormal breast cancer cells?
Which protein do cancer cells express on their surface to send a stop signal to hunting T-cells?
In what year did researchers first pioneer the spatial transcriptomics method to map gene expression in tissue sections?