Decoding the tumor genetic blueprint
Mapping the tumor microenvironment
High tech tools of reverse engineering
Designing the targeted counter attack
007skaty Cancer Cell Reprogramming
Turn off B-C-L-eleven-A and H-D-A-C to make those tough resistant cells respond again
007skaty Known as Herceptin, this monoclonal antibody blocks tumor growth signals and flags cancer cells for destruction by the patient's immune system
007skaty Reverse engineering breast cancer reveals fatal weaknesses in how tumor cells repair DNA.
007skaty Steer tiny cell scouts to discover how scientists reverse engineer breast cancer cures.
Living drugs: CAR-T cells are known as living drugs because they can multiply inside the patient's body and persist for years to prevent relapse.
A medical treatment that uses drugs to target specific genes and proteins involved in the growth and survival of cells. In 1998, the FDA approved trastuzumab, a groundbreaking treatment designed to combat HER2-positive breast tumors.
How do monoclonal antibodies like Herceptin find and attack breast cancer cells without harming healthy ones?
In what year did the FDA approve Herceptin, the first monoclonal antibody targeting HER2-positive breast cancer?
What is the name of the class of targeted drugs that block the backup DNA repair pathway in BRCA-mutant cancers?
What scientific concept describes killing a cell by disabling two pathways that are harmless when disabled individually?
Why is CAR-T therapy more challenging in solid tumors like breast cancer than in blood cancers?
What therapeutic strategy is designed to prevent tumors from developing drug resistance by blocking multiple pathways at once?