What is the primary function of the frequently mutated TP53 gene in
Chapter 1

The blueprint of a rogue cell

Chapter 2

Reading the enemy's master code

Chapter 3

Reprogramming the body's defenders

Chapter 4

The next frontier of precision weapons

Ch 1 · The blueprint of a rogue cell
007skaty

007skaty The biological mechanics of cellular rebellion and tumor growth.

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007skaty Metastasis Pathways

The collagen tracks, the collagen tracks They point the way out.

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Without internal constraints, the drive to grow becomes self-destructive.

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007skaty How genetic typos in our DNA cause cells to grow uncontrollably

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The mechanics of a cellular rebellion

007skaty Billions of daily cell divisions can fail, creating either localized benign tumors or invasive malignant tumors that spread throughout the body.

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The genetic typos in our code

007skaty Genetic typos in TP53 disable the cellular brakes that normally stop tumor growth.

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Tiny Tunnels
BETA

007skaty Navigate tiny tunnels to discover how scientists block cancer from spreading.

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Fun Fact

Dinosaur cancer: Fossil evidence shows that a Centrosaurus dinosaur living 76 million years ago suffered from aggressive bone cancer, proving cancer is ancient.

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Glossary
genome (noun)
The complete set of genetic material present in a cell or organism. In 2008, researchers successfully sequenced the first complete genome of an acute myeloid leukemia patient.

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Gossip

Which biological mechanism is the most fascinating?

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Quiz

Approximately how many cells divide in a healthy adult human body every single day?

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007skaty How growing tumors hijack the human bloodstream

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Quiz

What is the primary difference between a benign tumor and a malignant tumor?

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007skaty Cancer cells use dangerous pathways to spread through the body.

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Quiz

Which scientists won a Nobel Prize in 1989 for discovering oncogenes, the genes that promote cancer growth?

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Quiz

What is the primary function of the frequently mutated TP53 gene in human cells?

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Quiz

What is the name of the process where tumors recruit new blood vessels to supply themselves with oxygen?

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Quiz

According to researcher Judah Folkman's 1971 hypothesis, what is the maximum size a tumor can reach without its own blood supply?

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Quiz

Through which two primary biological transport networks do cancer cells travel to colonize other organs?

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Quiz

What percentage of cancer deaths are estimated to be caused by metastasis rather than the primary tumor?

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