Chapter 1
The science of freezing solid
Chapter 2
Surviving the extreme northern wilderness
Chapter 3
The great spring thaw
Chapter 4
Wood frogs and the future of medicine
YOUR GOAL
Master of Magic powers of the wood frog
Ch 1 · The science of freezing solid
torito Wood Frog Freezing Survival
When winter's chill begins to creep, Wood frogs freeze solid while they sleep!

torito Wood frogs accumulate high levels of urea to help protect their cells during freezing.
Fun Fact
Frog antifreeze: Wood frogs can survive with up to 65% of their body water completely frozen solid.
Glossary
cryoprotectant (noun)
A substance that protects biological tissue from damage during freezing. During winter hibernation, the wood frog floods its organs with glucose to prevent ice from destroying cells.
A substance that protects biological tissue from damage during freezing. During winter hibernation, the wood frog floods its organs with glucose to prevent ice from destroying cells.
Quiz
What chemical, normally excreted as waste, does the wood frog retain to help survive freezing?

