CRISPR as a Genetic Search Engine for Breast Cancer
Chapter 1

Decoding the tumor genetic blueprint

Chapter 2

Mapping the tumor microenvironment

Chapter 3

High tech tools of reverse engineering

Chapter 4

Designing the targeted counter attack

Ch 3 · High tech tools of reverse engineering
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007skaty CRISPR functions as a genetic search engine to locate specific genes

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007skaty AI Breast Cancer Pathology

Reading twenty-six patterns in the cells around the tumor, the AI predicts the path to heal.

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To find a system's vulnerability, we must test what it cannot survive without.

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007skaty Artificial intelligence algorithms identify microscopic cancer cells on digital biopsy slides.

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Growing miniature tumors in a dish

007skaty Cultivating 3D breast cancer organoids preserves a patient's unique genetic quirks, allowing rapid, personalized drug testing without risking safety.

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Zooming in with single-cell sequencing

007skaty Reverse engineering breast tumors requires analyzing billions of highly diverse cancer cells

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DNA Search Party
BETA

007skaty Search DNA strands for mutations to discover how scientists reverse engineer breast cancer cures.

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Fun Fact

Organoid biobanks: Scientists maintain frozen biobanks of patient-derived tumor organoids, allowing researchers worldwide to test new drugs on real human cancer models.

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Glossary
algorithm (noun)
A process or set of rules to be followed in calculations or other problem-solving operations, especially by a computer. In 2017, the international DREAM challenge crowdsourced machine learning algorithms to improve digital mammography interpretation.

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Gossip

Which high-tech tool is the most revolutionary?

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Quiz

What is the name of the 3D, miniature tissue models grown in labs from patient cells to mimic real tumors?

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007skaty Single-cell RNA sequencing examines the genes of individual cells.

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Quiz

What major advantage do 3D organoids have over traditional 2D cell cultures on flat plastic dishes?

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007skaty Scientists grow miniature breast cancer tumors inside laboratory dishes.

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Quiz

What critical problem does single-cell sequencing solve that traditional bulk sequencing overlooks?

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Quiz

Approximately when did single-cell RNA sequencing begin to be widely adopted to study cellular diversity in tumors?

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Quiz

How do researchers use CRISPR-Cas9 to identify new drug targets in breast cancer cells?

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Quiz

In what year did the discoverers of the CRISPR-Cas9 gene-editing tool win the Nobel Prize in Chemistry?

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Quiz

What type of artificial intelligence technology is trained on digital images to recognize cancer cells?

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Quiz

How does artificial intelligence primarily assist pathologists in evaluating breast cancer biopsy slides?

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