The blueprint of a rogue cell
Reading the enemy's master code
Reprogramming the body's defenders
The next frontier of precision weapons
007skaty Managing the Immune Storm
Calm the storm, calm the storm, block IL-6 so they still fight
007skaty By displaying PD-L1 proteins, cancer cells send a false do not attack signal to escape the body's primary immune soldiers.
007skaty Monoclonal antibodies block CTLA-4 and PD-1 proteins, releasing the immune system's natural brakes.
007skaty Match DNA sequences to learn how scientists genetically engineer our cells to fight cancer.
Living drug: Unlike traditional chemicals or radiation, CAR-T cells are alive and can survive inside a patient's body for over a decade to prevent cancer from returning.
What is the name of the protein on cancer cells that binds to T-cells to send a 'do not attack' signal?
Which immune cells act as the body's primary soldiers, scanning tissues to destroy abnormal cells?
What do checkpoint inhibitor drugs physically do to help the immune system fight cancer?
Which scientists won the Nobel Prize in Medicine in 2018 for discovering cancer therapy by inhibition of negative immune regulation?
Which specific cell-surface protein do the first approved CAR-T therapies target on leukemia cells?
In what year did the FDA issue its historic first approval for a CAR-T cell therapy?
Which anti-inflammatory drug is commonly used by doctors to treat severe cytokine release syndrome in CAR-T patients?