What is the name of the massive protein structure that guards the
Chapter 1

The locksmith's secret language

Chapter 2

Digital fortresses and code

Chapter 3

Nature's ultimate gatekeepers

Chapter 4

Gatekeepers of myth and history

Ch 3 · Nature's ultimate gatekeepers
007skaty

007skaty How viruses bypass host cell membranes to replicate

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007skaty A selective phospholipid bilayer membrane controls what enters every living cell.

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007skaty The Nuclear Pore Complex

A thousand cargos pass the gate each second (Each second!) / You need a signal key to slide on through (To slide on through!)

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Unlock the Brain
BETA

007skaty Match the master keys to mental locks to learn how your brain processes information.

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The selective cell membrane

007skaty While small molecules like oxygen and water cross the semi-permeable membrane freely, larger charged molecules require specialized transport proteins to enter

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Quiz

What is the primary structural component of the cell membrane that acts as a barrier?

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Quiz

How do larger molecules cross the semi-permeable cell membrane?

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The defenses that keep us safe also block the help we need.

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How viruses pick the cellular lock

007skaty Host cells accidentally open their gates when viral proteins bind to surface receptors

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Quiz

Which human cell receptor does the SARS-CoV-2 virus target to unlock and enter cells?

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Quiz

What viral component acts as a molecular key to bind to host cell receptors?

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Fun Fact

Water channels: The cell membrane uses specialized channels called aquaporins that allow up to three billion water molecules to pass through per second, one by one.

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Quiz

Approximately what percentage of small-molecule drugs are blocked by the blood-brain barrier?

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Quiz

What type of cells form the tightly packed walls of the blood-brain barrier?

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Glossary
kisspeptin (noun)
A neuropeptide hormone that plays a crucial role in regulating reproductive function and initiating the onset of puberty. In 2003, scientists discovered that mutations in the GPR54 receptor block the hormone, halting human sexual maturation.

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Quiz

What is the name of the massive protein structure that guards the entrance to the cell's nucleus?

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Quiz

Which helper protein acts as a chaperone key to guide cargo through the nuclear pore complex?

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Gossip

If you could microscopic-travel?

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Gossip

Which cellular function is cooler?

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