Decoding ancient remedies
Copying nature's chemical weapons
Working backward from the disease
The digital drug revolution
007skaty Spike Protein Neutralization
We program a protein to block out the key, And bind to the spike so the cells can stay free.
007skaty Scientists target viruses and cancers by finding disease-causing receptors or enzymes and designing matching chemical keys to fit them.
007skaty Designed molecules physically jam the enzyme machinery to stop the virus from replicating.
007skaty Reprogram rogue cells with custom proteins to learn how scientists reverse engineer targeted medicines.
Lock and key: The lock-and-key model of enzyme action was first proposed in 1894 by German chemist Emil Fischer, long before we could see proteins.
An observational study that compares individuals who have a specific medical condition with those who do not. In 1950, Richard Doll and Austin Bradford Hill used this design to link smoking with lung cancer.
What is the term for the specific site on a protein where a drug molecule binds to exert its effect?
Which technique uses X-rays to determine the precise 3D shape of a target protein's lock?
What is the name of the first FDA-approved HIV protease inhibitor, released in 1995?
What type of enzyme does Gleevec inhibit to prevent cancer cells from multiplying?
Which part of the SARS-CoV-2 virus do monoclonal antibody treatments typically target to block infection?