
The gut hormone revolution
The vanishing muscle mystery
Muscle as our metabolic super-engine
The new rules of training
coach Bone Density Decline
As the weight falls fast, the bones grow thin, we have to lift to hold them up.

coach Standard scales hide the loss of vital lean mass like muscle and bone by only measuring your total body weight.

coach Strength training prevents the body from treating muscle as fuel during GLP-1 therapy.

coach Defend your muscles from shrinking to discover why protecting strength matters more than ever.
Weight composition: In the landmark STEP-1 clinical trial for semaglutide, participants lost an average of about 10% of their total lean body mass alongside their fat loss.
The progressive loss of skeletal muscle mass and strength, typically associated with aging or inactivity. Clinical trials show that up to forty percent of weight lost from semaglutide is skeletal muscle.
What percentage of total weight lost during rapid weight loss can come from lean mass like muscle?
Why does a severe caloric deficit cause the body to break down active muscle tissue?
Why is accelerated muscle loss particularly dangerous for older adults on GLP-1 therapies?
What is the medical term for the loss of skeletal muscle mass, strength, and function?