The body's defense force
Releasing the biological brakes
Living drugs and cellular engineers
The future frontier of healing
YOUR GOAL
Master of The immunotherapy revolution
futura Releasing the biological brakes
Your own body's power, Starts seeing the way. Those biological brakes, Are off, come what may.
futura Dr. Tasuku Honjo discovered the PD-1 protein, leading to highly effective therapies for multiple cancer types.
futura Immunologist Jim Allison developed an antibody that blocks the CTLA-4 brake, letting T cells attack tumors.
futura Direct your immune cells to master how they fight disease without attacking healthy cells.
Nobel prize celebration: To celebrate his 2018 Nobel Prize, Jim Allison, a talented harmonica player, performed live with his blues band, the Checkpoints, at the Nobel gala.
A type of drug that blocks proteins preventing the immune system from attacking cancer cells. In 2018, James P. Allison and Tasuku Honjo won a Nobel Prize for pioneering this therapy.
What was the name of the first FDA-approved checkpoint inhibitor drug, approved in 2011 to treat advanced melanoma?
Why did Jim Allison and Tasuku Honjo jointly win the Nobel Prize in Physiology or Medicine in 2018?
Which type of cancer was the first to show dramatic, long-term remission rates during early clinical trials of checkpoint inhibitors?
What is a common side effect of checkpoint inhibitor drugs due to the "brakes" being removed from the immune system?
Which American immunologist discovered that blocking the CTLA-4 checkpoint could unleash T cells to destroy tumors in mice?
In 1992, Japanese researcher Dr. Tasuku Honjo discovered which critical immune checkpoint protein?